Dienophile LUMO

Chem 109C

Organic Chemistry, Spring 2005

Diene HOMO

Lecturer:

Dr. Kalju Kahn
Office: PSB-N 1511
Office hours: Tue 12:30 - 1:30 PM ; Fri 12:00-1:00 PM or by appointment
Phone: 893-6157
Office hours: Tue 12:30- 1:30 PM; Fri 12:00-1:00 PM or by appointment E-mail: kalju@chem.ucsb.edu
Web site: http://www.chem.ucsb.edu/~kalju

Head TA:

Alex Lippert
Office: PSB-N 2126
E-mail: alippert@chem.ucsb.edu
Phone: 893-7418
Office hours: Tue, Thu: 4:00 - 5:00 PM in Chem 1668 or by appointment

Mission statement

Chem 109C is the last course of a three-course sequence (Chem 109A-B-C). The Chem 109 sequence provides the students fundamentals of organic chemistry and is mainly intended for students in the field of chemistry and biology. The current course, Chem 109C, has three foci:

  1. Exploration of molecular orbital (MO) theory in predicting chemical reactivity. We will review basic concepts of the MO theory and discuss how orbital symmetry considerations allow predicting stereochemical outcomes of pericyclic reactions.
  2. Structure and reactions of organic compounds found commonly in living organisms: carbohydrates, lipids, amino acids, peptides, nucleotides, nucleic acids, and coenzymes. These topics make up the bulk of the course
  3. Application of organic chemistry in design and synthesis of drugs and polymers. Substituent effects on reactivity and ionization of substituted benzenes will be discussed in relation to quantitative structure-activity relationships (QSAR).

Schedule

      Lecture:        TR 5:00-6:15   Place:	Chem 1179
Syllabus General information about the course PDF
Textbook "Organic Chemistry" by Paula Bruice, 4th ed. Website
Scores Point Distribution after Quiz 1 Graph
Scores Point Distribution in Midterm 1 Graph
Scores Point Distribution in Midterm 2 Graph
Scores Point Distribution before the Final Graph
Scores Point Distribution in the Final Exam Graph
Scores Point Distribution: Total Score in the Course Graph
Exams Midterm I Preparation Guide PDF
Exams Midterm II Preparation Guide PDF
Exams Final Preparation Guide PDF
Exams Sample Exam (old Chem109A) PDF
Exams Midterm I Key PDF

Lecture-Related links

Week 1 Diels-Alder Reaction Link
Week 1 Electrocyclic Reactions Link
Week 2 Biochemistry of Carbohydrates (Chem 142A lecture slides) PDF
Week 3 Biochemistry of Amino Acids (Chem 142A lecture slides) PDF
Week 4 Biochemistry of Peptides (Chem 142A lecture slides) PDF
Week 5 Enzyme Catalysis (Chem 142A lecture slides) PDF
Week 5 Protein Structures Illustrated Link
Week 7 Lipids (lecture slides) PDF
Week 8 Nucleic Acids (lecture slides) PDF
Week 9 Principles of Drug Discovery and Design PDF
Week 10 Medicinal Chemistry PDF

Vitamin Problems

Week 1 UV-Vis, Conjugated Systems, Solvatochromic Shifts, Diels-Alder Reaction PDF
Week 2 Pericyclic reactions: Cope with cycloaddition PDF
Week 3 Carbohydrates: Properties and Analysis PDF
Week 5 Amino Acids, Proteins, Peptides PDF
Week 6 Catalysis PDF
Week 7 Cofactors and Lipids PDF
Week 9 Nucleotides and Drug Design PDF

Useful organic chemistry links

Organic Chemistry Virtual Text at Michigan State University
Ralph Logan's homepage, and especially his Organic Chemistry Support Materials (North Lake College)
Richard Thies: organic chemistry course at Oregon State University
Turro/Rusay Web-ster Organic Chemistry (Columbia and Berkley)
IUPAC Nomenclature Home Page: Advanced aspects of nomenclature, good stereochemistry section
NIST Chemistry WebBook: Vast amounts of data on organic compounds

UCSB links

UCSB General Catalog
UCSB Campus Map
UCSB Gold Login
UCSB Umail Access
UCSB Environmental Health and Safety


Course materials by Dr. Kalju Kahn, Department of Chemistry and Biochemistry, UC Santa Barbara. ©2005