Chem 108, Organic Chemistry

 course syllabus

 carbohydrate chemistry on the web

problem set 1 (answers handed out in class)

problem set 2 (answers handed out in class)

 Upcoming review session

     Problem set 3 and some words of advise ... (answers handed out in class)

 A web-based primer on amino acids, peptides, proteins, and enzymes

     problem set 4 (answers will be handed out in class; also available outside of room 3132 of the Chem Building ... just outside of the head TA's office)

     Problem set 5 (amino acids; peptides - good preparation for an exam)  Answers will be handed out in class.

      Problem set 6 - posted following the lecture of Friday, 10/26/01.   Commentary:  "Do you need to know the material discussed in class today for an exam?"  Well … here are a few questions that readily come to mind.  While they do not refer specifically to the "bacteria problem" posed in the lecture, they do refer to the chemistry germane to the discussion.  So … I guess the answer to the question is - yes, but not necessarily in precisely the same form.  I hope you have some fun with these.

 A fine web site re serine proteases

 ... chymotrypsin in all its splendor

    An "overview problem set" [aka "exam prepper"] to assist in studying for the Nov. 9 exam.

Review session this Thursday (11/8/01) in Phelps 1160, from 6:30 to 8:30 pm.

 ... list of amino acids that will be appended to the exam for your use.

 Problem set 9 - two "coenzyme questions"

 thymidylate synthase - treatment of some forms of cancer

Problem set 10 - cofactors and reactions

 Problem set 11 - nucleic acids, etc

 Genetic code (codons) - a web link

 Problem set 12 (DNA, RNA, ...); set 13 to come (an 'exam prepper')

 Final exam prepper - problems designed to serve as a course overview.

 Review session for final exam - when? where?

 amino acids, DNA/RNA bases, cofactors - as on final exam. Codon table will also be provided - but not here. For now, please check your text (p. 1086 of 3rd edition, Table 25.2).

Am not sure whether I did, but just in case I misstated myself on one of the solution sets, please read the following:  The DNA coding sequence (the sense strand ... the strand to be copied) is complementary to the template strand.  The template strand is transcribed by the single-stranded mRNA ... by forming RNA's complement to the template.  As a result, the mRNA is identical to the sense strand, except for the substitution of U in place of T, and for the fact that the sugar portion of the sequence contains OH groups at C2'.  The mRNA contains the code that indicates which amino acid is to appear in the protein sequence.  For each triplet [codon] of the mRNA, there will be a complementary anticodon sequence that appears in the anticodon loop of the tRNA to which the amino acid is attached.  The tRNA translates the mRNA from the language of U, A, C, and G, into the language of amino acids.

Comments regarding the final exam:  You will find appended to each exam the structure of key amino acids (you provide the stereochemistry), as well as the structure of the enzyme cofactors, the structure of DNA/RNA bases, and a table corresponding to the codon-amino acid correlations.  The names of the enzyme cofactors and the names of the bases will not been provided.

 "The RNA World" ... some leisure reading
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 Jon, Chheduk man, RDL, and Sanjay - near 18,000 feet - end of June 2001 - Nepal

 Mt. Everest